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Thumb monkey

Thumb monkey (Picture 1)

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Thumb monkeys are smaller non-human primates that originate in the tropical rain forests of northeastern Brazil near the Atlantic Ocean. Therefore, it is also called the New World Monkey. The thumb monkey belongs to the family of long-tailed monkeys. Wild thumb monkeys mainly inhabit the upper canopy of tropical rain forests or tropical forests and grasslands. They rarely mobilize on the ground. They usually search for food during the day and sleep in tree holes at night. Because they live in tropical rain forests in South America, they must maintain high temperatures and humidity in the laboratory feeding area. Generally, the room temperature should be controlled at 24 ~ 30 ℃, and the relative humidity should be 50 ~ 80%. Thumb monkeys have a mixed diet, and in the wild they feed on the exudates of insects, spiders, small vertebrates, bird eggs, lizards, birds or trees.

The thumb monkey has a small tail, a tangled tail, and a long hair at the end. The head is large and bare or has sparse hair, no cheek pouch, 32 teeth, wide nasal septum, left and right nostrils open to both sides, so it belongs to the family of broad-nosed monkeys. The coat is velvet-like, with various colors, including silvery white, red, black brown, black gray, and black. Except for the big toe, the toes are sharp claws and no nails. Thumb monkey is a non-seasonally reproduced animal with an average gestation period of 144 days, sexual maturity of 14 months, and sexual cycle of 16 days, including 6 days of follicular phase, 10 days of luteal phase, and no menstrual bleeding. It can be artificially propagated in a cage, 1 to 3 litters per baby, and weaned in 2 to 3 months. The probability of twins is about 80%, and the survival rate is high.

Thumb monkeys are widely studied in the biomedical field, especially in reproductive biology, neuroscience, pharmacokinetics and drug toxicity screening, stem cell research, autoimmune diseases, animal models of infectious diseases, such as dengue fever. Great potential. At present, thumb monkeys have been used as animal models for a variety of biological research, including neuroscience system research, assisted reproductive technology research, and infection disease research, especially for many chronic diseases, including Lassa fever, stroke, and Parkinson's disease. Disease, multiple sclerosis, Huntington's disease, Alzheimer's disease, and more. In recent years, research on non-human primate genetically modified animals including thumb monkeys and macaques has gradually become a new research hotspot.

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